NDC Search API

Search the FDA NDC Directory for drug products by name, ingredient, strength, and more.

Endpoint

GET /v1/ndc/search

Quick Start

Node.js

import { Fhirfly } from "@fhirfly-io/terminology";

const client = new Fhirfly({ apiKey: "YOUR_API_KEY" });

// Search for metformin tablets
const results = await client.ndc.search({
  q: "metformin",
  dosage_form: "TABLET"
});

console.log(`Found ${results.total} products`);
for (const item of results.items) {
  console.log(`${item.ndc}: ${item.name}`);
}

Parameters

Text Search

At least one text search parameter or standalone filter is required.

Parameter	Description	Example
`q`	General text search across all fields	`q=advil`
`name`	Search product name	`name=lipitor`
`brand`	Search brand name	`brand=tylenol`
`generic`	Search generic name	`generic=acetaminophen`
`ingredient`	Search active ingredient (standalone)	`ingredient=ibuprofen`

Filters

Parameter	Type	Description	Example
`strength`	string	Drug strength (parsed flexibly)	`200mg`, `10mg/5ml`
`dosage_form`	string	Dosage form	`TABLET`, `CAPSULE`
`route`	string	Administration route	`ORAL`, `TOPICAL`
`labeler`	string	Manufacturer name	`Pfizer`
`product_type`	enum	`otc`, `rx`, or `all`	`rx`
`dea_schedule`	enum	DEA schedule	`CII`, `CIII`, `none`
`marketing_category`	string	FDA approval type	`nda`, `anda`
`pharm_class`	string	Pharmacological class	`Anti-Inflammatory`
`is_active`	boolean	Currently marketed	`true`
`has_rxcui`	boolean	Has RxNorm mapping	`true`
`rxcui`	string	Specific RxCUI (standalone)	`197806`

Pagination & Response

Parameter	Default	Max	Description
`limit`	20	100	Results per page
`page`	1	100	Page number
`shape`	compact	—	`compact`, `standard`, `full`
`sort`	relevance	—	`relevance`, `name`, `labeler`

Example Response

{
  "facets": {
    "dosage_form": {
      "TABLET": 186
    },
    "product_type": {
      "HUMAN PRESCRIPTION DRUG": 170,
      "DRUG FOR FURTHER PROCESSING": 16
    },
    "route": {
      "ORAL": 170
    }
  },
  "has_more": true,
  "items": [
    {
      "active": true,
      "generic": "Metformin ER 500 mg",
      "labeler": "Aphena Pharma Solutions - Tennessee, LLC",
      "name": "Metformin",
      "ndc": "71610-613",
      "type": "product"
    },
    {
      "active": true,
      "generic": "Metformin ER 500 mg",
      "labeler": "A-S Medication Solutions",
      "name": "Metformin",
      "ndc": "50090-6515",
      "type": "product"
    }
  ],
  "limit": 2,
  "meta": {
    "legal": {
      "attribution_required": false,
      "citation": "FDA NDC Directory. Accessed 2026-01-28 via FHIRfly.",
      "license": "public_domain",
      "source_name": "FDA NDC Directory"
    }
  },
  "page": 1,
  "total": 186,
  "total_capped": false
}

Use Cases

Find OTC Pain Relievers

Node.js

const results = await client.ndc.search({
  ingredient: "ibuprofen",
  product_type: "otc",
  is_active: true
});

Find Controlled Substances

Node.js

const results = await client.ndc.search({
  q: "oxycodone",
  dea_schedule: "CII"
});

Find by Strength

Node.js

// Strength parsing handles various formats
const results = await client.ndc.search({
  q: "metformin",
  strength: "500mg"  // Also accepts: "500 mg", "0.5g"
});

Find Products with RxNorm Mapping

Node.js

// Find products mapped to a specific RxCUI
const results = await client.ndc.search({
  rxcui: "197806"
});

NDC search returns these facets:

Facet	Description
`dosage_form`	Distribution by dosage form
`product_type`	Distribution by OTC vs prescription
`route`	Distribution by administration route

Valid Values

DEA Schedules

CI, CII, CIII, CIV, CV, none

Marketing Categories

nda, anda, bla, otc monograph drug, otc monograph final, otc monograph not final

Product Types

otc, rx, all

Required Scope

ndc.search

NDC Search API

Endpoint

Quick Start

Parameters

Text Search

Filters

Example Response

Use Cases

Find OTC Pain Relievers

Find Controlled Substances

Find by Strength

Find Products with RxNorm Mapping

Facets

Valid Values

DEA Schedules

Marketing Categories

Product Types

Required Scope

See Also

NDC Search API

Endpoint

Quick Start

Parameters

Text Search

Filters

Pagination & Response

Example Response

Use Cases

Find OTC Pain Relievers

Find Controlled Substances

Find by Strength

Find Products with RxNorm Mapping

Facets

Valid Values

DEA Schedules

Marketing Categories

Product Types

Required Scope

See Also

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